Antimuscarinics for overactive bladder

As I would have expected, main SEs are dry mouth and constipation.  There is some evidence that solifenacin, extended release oxybutinin, and extended release tolterodine are more effective than the other drugs and that fesoterodine may be the most effective.  Beware of acute angle closure glaucoma, myasthenia gravis, severe UC, toxic megacolon, and intestinal obstruction – all are CI to antimuscarinics.

(From BMJ 14th April 2012)

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About Dr Sarah

I'm a GP with a husband and two young children.
This entry was posted in BMJ, Incontinence, Medication, Urology. Bookmark the permalink.

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