I was taught that prednisolone courses for COPD exacerbations should be two weeks plus a wean-off, but have noticed that most people seem to use five days. The controversy is now resolved – the REDUCE trial, an RCT in Switzerland, compared 5-day and 14-day courses of 40 mg prednisolone in exacerbations of severe COPD and found the former to work just as well.
Nitrofurantoin can apparently be given as a 100 mg dose bd, which makes life vastly easier.
If giving prophylactic antibiotics for recurrent UTI in women, have a trial off the antibiotics after six months to see whether they’re still required.
(BMJ 1st June 2013, 7910)
A Spoonful Of Sugar 