Prescribing tips

I was taught that prednisolone courses for COPD exacerbations should be two weeks plus a wean-off, but have noticed that most people seem to use five days. The controversy is now resolved – the REDUCE trial, an RCT in Switzerland, compared 5-day and 14-day courses of 40 mg prednisolone in exacerbations of severe COPD and found the former to work just as well.

Nitrofurantoin can apparently be given as a 100 mg dose bd, which makes life vastly easier.

If giving prophylactic antibiotics for recurrent UTI in women, have a trial off the antibiotics after six months to see whether they’re still required.

(BMJ 1st June 2013, 7910)


About Dr Sarah

I'm a GP with a husband and two young children.
This entry was posted in BMJ, COPD, Credits 2013, Infectious Diseases, Medication, Respiratory. Bookmark the permalink.

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