We’ve just been sent some information about Efudix use in general practice, and I wanted to write down the main points:
- If an area has multiple solar keratoses, the whole area (not just the individual keratoses) should be treated, as it’s a high-risk area – Efudix is licenced for areas up to 23 x 23 cm. (Not sure I’d have the nerve to do that, though!)
- It’s not necessary to wear gloves to apply Efudix, but hands should be washed thoroughly afterwards.
- It should be applied thinly using the fingertips (I guess I knew that, but it’s useful to have the actual practicalities reinforced). Cotton buds can be useful to apply to small areas.
- If you apply Efudix to skin without visible SKs (see above) and it goes red and inflamed, apparently that’s a sign of non-visible changes in the skin.
- Don’t expose skin to sunshine while undergoing treatment.
- It should be applied twice a day for three weeks. The skin inflammation should then settle over the next three weeks, with clearance of the sun-damaged skin occurring over weeks 6 – 16.
- GP review should be 12 weeks after completing the course (i.e. around 15 weeks after starting it). However, the patient should come for review sooner if the soreness/discomfort during treatment is excessive, the skin is becoming ulcerated or scabbed, or pus appears (which can mean infection).
(Notes taken from presentation by Dr Ben Kay, DPD MSc practical dermatology, Harcourt Medical Centre. Any errors in transcription of his presentation are probably mine.)