Category Archives: HRT

Managing menopause

Posted on August 31, 2019 by

(Notes from BMJ module) From 45 yrs onwards, menopause/perimenopause can be diagnosed on history only. FSH or other blood tests are not actually helpful in diagnosis in the >40s because of the wide fluctuation in levels in the perimenopause. FSH … Continue reading →

Posted in Gynaecology, HRT | Leave a comment

HRT and heart disease

Posted on October 26, 2017 by

Well, we have an update on the days of the Million Women Study (though it’s still a cool trial name). Much of the data available then were from women starting HRT in their mid-sixties, and this skewed the data. It … Continue reading →

Posted in Gynaecology, HRT | Leave a comment

HRT

Posted on August 6, 2016 by

Who can have it? Several of the contraindications to combined oral contraception are not contraindications to HRT; in particular, being a smoker over 35 is not considered a contraindication at all, even to oral HRT. I suppose that one was … Continue reading →

Posted in Gynaecology, HRT, Uncategorized | Leave a comment

HRT post MI

Posted on April 16, 2014 by

Surprisingly, it appears to be OK. Hulley et al. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. JAMA 1998; 280: 605 – 13, and follow-up Grady et al, Cardiovascular disease outcomes during … Continue reading →

Posted in Cardiovascular, HRT | Leave a comment

Menopausal symptoms

Posted on January 30, 2013 by

  Lifestyle measures: Healthy diet/regular exercise/avoiding smoking/reducing alcohol, caffeine, and stress, can all help to reduce symptoms to some extent.   Therapy for hot flushes:   HRT – 77% reduction relative to placebo, plus significant reduction in symptom severity. SSRIs … Continue reading →

Posted in Credits 2013, Gynaecology, HRT, Medication | 1 Comment

Snippets

Posted on December 27, 2012 by

Ovestin vaginal cream does not increase circulating oestradiol, and thus can be considered for treatment of vaginal dryness in women who’ve had breast cancer. Evidence varies on whether systemic oestrogen increases recurrence risk (HABIT trial vs. Stockholm trial) but it’s … Continue reading →

Posted in BJGP, Cardiovascular, HRT, Hypertension, Medication | 1 Comment

Sundries

Posted on April 30, 2012 by

It may be worth starting metformin immediately on diagnosis of DM, without waiting to see whether dietary treatment works. One study found that starting metformin within three months of diagnosis was associated wtih a reduced rate of monotherapy failure a … Continue reading →

Posted in Alternative medicine, BMJ, Cardiovascular, Credits 2012, Dementia, Diabetes, HRT, Migraine, Paediatrics | Leave a comment