Category Archives: Haematology

Antiplatelet therapy with anticoagulation therapy?

A BMJ article addressing an important and common question; in patients who have an indication for antiplatelet therapy plus an indication for anticoagulant therapy, should we give both or just one? In most cases, we should just give the anticoagulant, … Continue reading

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Haemolysis markers

Reticulocyte count up Reduced haptoglobin Raised LDH (BMJ Learning module on jaundice)

Posted in Haematology, Investigations, Lab results | Leave a comment

Easy bruising

I normally just use a full blood count to investigate easy bruising; I’ve ummed and ahhhed about getting a clotting screen as well, but it seems like overkill to me. However, the authors of an article in the latest BMJ … Continue reading

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Neutropenia

An old article; unearthed an old BMJ I’d saved but never got round to making notes on. BMJ 2014;349:g5340. Neutropenia is defined as a neutrophil count <1.5 x 10^9. It’s classified in increments of 0.5 (1 – 1.5 is mild, … Continue reading

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Macrocytosis

In response to a DEN that came up with a patient’s results, I’ve been refreshing my memory on the causes of macrocytosis. Briefly, these are: Physiological – macrocytosis is normal in pregnancy (usually mild but not impossible for it to … Continue reading

Posted in Credits 2015, Haematology, Lab results | Leave a comment

MGUS, myeloma, and other paraprotein-related problems

Globulins: Proteins produced by plasma cells in the bone marrow. Serum globulin level is the difference between total protein level and albumin level. Polyclonal increase in plasma cells: increase in globulin (which may show up as increased total protein with … Continue reading

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VTE – NICE guidance

Everyone with suspected VTE is now supposed to have some sort of investigation. This is where the ability to draw flowcharts would be really helpful: Wells 2 or above – Doppler within 4 hours, or, if that’s not possible, get … Continue reading

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