Category Archives: Medication

Bits and bobs

Useful bunch of motley learning points from the 15th April BMJ: A double-blind trial reported in NEJM has looked at the effects of treating borderline thyroid results (raised TSH with normal T4) in the elderly. It didn’t show any benefit … Continue reading

Posted in BMJ, Cardiovascular, Credits 2017, Endocrinology, Hypertension, Medication, Paediatrics, Thyroid | Leave a comment

Snippets

A few quick snippets from the 19th Nov BMJ: Duloxetine increases the risk of adverse psychiatric events – anxiety, agitation, self-harm, psychotic behaviour – by more than five times, according to a new Nordic Cochrane Centre meta-analysis although this article … Continue reading

Posted in Incontinence, Ligaments, Medication, Minor but annoying | Leave a comment

Diabetes presentation

Went to the practice clinical meeting, which was about diabetes this time and mainly focused on new diabetes drugs, as well as going over the NICE guidelines. The meds covered were incretin-based therapies (GLT-1 agonists and DPP-4 inhibitors) which I … Continue reading

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Polypharmacy

In patients who are on an anticoagulant, there is no evidence to support adding an antiplatelet agent, and SIGN and NICE guidelines now say that this is not recommended. We don’t have data on whether this applies to patients who … Continue reading

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Triptans

These divide into two groups: Sumatriptan, Rizatriptan, Zolmitriptan, Eletriptan and Almotriptan have a higher speed of onset. Naratriptan & Frovatriptan have a lower side-effect profile, and also possibly less chance of headache recurrence. Interestingly, someone who hasn’t responded to one … Continue reading

Posted in Medication, Migraine, Neurology | Leave a comment

Warfarin vs. NOACs for non-valvular atrial fibrillation

Interesting new article from the BMJ comparing warfarin with NOACs in patients with non-valvular atrial fibrillation, using data from large-scale Danish databases. The findings were: Rivaroxaban is marginally more effective than warfarin at preventing ischaemic strokes or systemic embolism, but … Continue reading

Posted in Anticoagulants, Credits 2016, Medication | Leave a comment

Rational prescribing

From our CCG’s review of evidence (Rational Prescribing, Sept 2015): On current evidence (which admittedly is somewhat limited), there is no statistically significant benefit from treating Stage 1 hypertension (160/100 or less) Aiming for an HbA1c level of 7.0% vs. … Continue reading

Posted in Credits 2016, Diabetes, Hypertension, Medication, Nephrology | Leave a comment