Category Archives: Medication

Snippets

Bits and bobs from the BMJ of 9th September: A systematic review in PLoS Medicine found gabapentin and pregabalin to be not particularly helpful with chronic low back pain; any benefits from them were outweighed by the risk of side-effects … Continue reading

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COPD algorithm

This is our practice algorithm for COPD treatment: Treat intermittent symptoms with a SABA. If more severe, differentiate between low-risk and high-risk patients. Low-risk patients are those with: FEV1 >50% <2 exacerbations/yr For low-risk patients: First-line treatment: LAMA If symptoms … Continue reading

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Refractory opioid-induced constipation

As anyone with even a smattering of palliative care knowledge should be aware, opiates typically cause constipation and a laxative should typically be co-prescribed. This week’s BMJ has a useful tip on what to do about opioid-induced constipation that is … Continue reading

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BRONJ (bisphosphonate-related osteonecrosis of the jaw)

The latest BJGP carries an article about this. Recommended management from the GP point of view: Asymptomatic BRONJ (exposed bone with no pain or evidence of local infection): Routine max-facs referral Antimicrobial mouth rinse, such as chlorhexidine 0.12% Pain/evidence of … Continue reading

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Snippets

Some interesting bits and bobs in the latest BMJ: The three most effective NSAIDs for hip and knee osteoarthritis appear to be, in descending order, diclofenac, etoricoxib, and rofecoxib. Now, of course, that’s of limited use, given the high risk … Continue reading

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Steroids – not all that useful for sore throats

There’s been some evidence in the past that steroids might be of help for sore throats, so it was interesting to see a JAMA study on the subject mentioned on Richard Lehman’s blog page. Comparison of a single 10 mg … Continue reading

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Treatment of urinary tract infection in pregnancy

A couple of useful points from a BMJ article: Nitrofurantoin is now considered safe in all three trimesters, but not at term; it can increase the risk of haemolysis Trimethoprim is considered safe after the first trimester Amoxicillin and cefalexin … Continue reading

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